Limited information is available concerning the content of minerals in durum wheat grown in the northern US. The objective of this research was to determine the content of macronutrient and micronutrient minerals in durum wheat cultivars that have been grown over the past 60 years in North Dakota. Thirty-two historic cultivars of durum wheat were sown and harvested from four replicate blocks of a field experiment established near Langdon, ND in 2014. Clean grain was ground and analyzed for ash content (measured by oven method) and eight minerals including Ca, Cu, Fe, K, Mg, Mn, Se, and Zn. Mineral composition and content were determined by using ICP-MS. Durum wheat cultivars differed in content of four minerals. The minerals and content range were Ca (45.0-63.8 µg/g), Mg (273.3-329.9 µg/g), Mn (6.02-8.66 µg/g) and Zn (4.94-6.87 µg/g). There was no relationship between year of cultivar release and mineral content. In general, ‘Ben’ and ‘Joppa’ had low contents while ‘Monroe’, ‘Munich’ and ‘Ward’ had high contents of individual minerals. The other four minerals, Cu, Fe, K, and Se, did not differ among cultivars which had average concentrations of 0.78, 8.90, 735.34, and 0.69 µg/g, respectively. People are commonly deficient in five minerals, Ca, Mg, K, Fe, and Zn. These results indicate phenotypic differences exist among durum cultivars for Ca, Mg, Mn, and Zn. These differences could be used to breed for increasing mineral contents for Ca, Mg, and Zn.