Cereal Chem. 70:364-366   |  VIEW ARTICLE

NOTE: Lipidemic Responses in Rats Fed Flaxseed Oil and Meal.

G. S. Ranhotra, J. A. Gelroth, B. K. Glaser, and P. S. Potnis. Copyright 1993 by the American Association of Cereal Chemists, Inc. 

In a six-week study, diets prepared with full-fat flaxseed meal (FM), defatted-FM (restored to full-fat level with a hard fat or isolated flaxseed oil [FO]), or just FO were compared for their effect on blood lipid levels. Hypercholesterolemic rats were used as the test model. FM greatly negated the adverse effect of hard fat (hydrogenated soybean oil) on serum total cholesterol (CH) and serum non high-density-lipoprotein CH. FM also accentuated the CH-lowering effect of isolated FO. Liver CH levels were quite elevated, especially in rats fed the diet not containing FM. Liver lipid levels ranged between 16 and 31%. Serum triglyceride levels were in the normal range and no lowering effect due to FM or FO was observed.